Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

E Williams; B Zhang; EPF Chow; S Chea; TR Phillips; K Maddaford; M Krysiak; Y Nong; H Stefanatos; S Pasricha; CK Fairley; DA Wiliamson

Journal article

Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

E Williams, B Zhang, EPF Chow, S Chea, TR Phillips, K Maddaford, M Krysiak, Y Nong, H Stefanatos, S Pasricha, CK Fairley, DA Wiliamson

Antimicrobial Agents and Chemotherapy | AMER SOC MICROBIOLOGY | Published : 2022

DOI: 10.1128/aac.00042-22

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Abstract

Improved treatment and prevention strategies, such as antimicrobial mouthwashes, may be important for addressing the public health threat of antimicrobial-resistant Neisseria gonorrhoeae. Here, we describe the activity of seven common antibacterial mouthwashes and antiseptics against N. gonorrhoeae isolates, incorporating the use of a human saliva test matrix. Our data demonstrate that antibacterial mouthwashes and antiseptics vary in their ability to inhibit the in vitro growth of N. gonorrhoeae and saliva may impact this inhibitory activity.

University of Melbourne Researchers

Eric Chow Author

Shivani Pasricha Author

Deborah Williamson Author

Related Projects (1)

APPLYING PATHOGEN GENOMICS TO THE PREVENTION AND CONTROL OF ANTIMICROBIAL RESISTANCE

Antimicrobial resistance (AMR) is a huge threat to public health, both in Australia and globally. In some instances, having an AMR infection..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

E.W. is supported by a National Health and Medical Research Council (NHMRC) Postgraduate Scholarship (GNT2005380). E.P.F.C. is supported by an NHMRC Emerging Leadership Investigator Grant (GNT1172873). C.K.F. is supported by an NHMRC Leadership Investigator Grant (GNT1172900). D.A.W. is supported by an NHMRC Investigator Grant (APP1174555).